How Fasting & the Keto Diet Actually Fight Cancer | Dr. Thomas Seyfried, PhD

How Fasting & the Keto Diet Actually Fight Cancer | Dr. Thomas Seyfried, PhD

July 20, 2019 16 By William Morgan


As you might know, the Ketogenic Diet is a
very popular topic here at The Truth About
Cancer.
It is a great diet to fight inflammation in
your body, if done correctly.
Dr. Thomas Seyfried who’s a specialist on
this topic talks more in this short video
about how fasting and the Keto diet may help
fight cancer.
Take out your pencils & notebooks and listen
carefully – you’ll want to take notes!
So, we have here normally epithelial cells.
Now, these cells can get damaged from any
one of the oncogenic paradox issues, they
start to proliferate, they start to increase
in the microenvironment.
Cells of our immune system now come in because
they see
this as a wound.
They have wound healing capabilities.
The macrophages throw out growth factors and
cytokines to put the wound out, but in so
doing it makes these blue cells grow even
faster.
So, our own bodies have a counteractive, we’re
fighting against each other.
They’re doing an inappropriate thing, but
they’re programmed to do that.
These cells will actually fuse with some of
the cells to help put out the fire, these
macrophages, and in so doing they dilute their
normal mitochondria in the cytoplasm.
Now, these macrophages now become corrupted.
These are the most powerful cells in our body,
they evolved to kill bacteria and keep us
healthy from the environment.
This is like the police department and the
militia being corrupted in your own society.
Bad problem, rogue macrophages.
They’re programmed to enter and exit the
circulatory system, they’re programmed to
shut down immune responses, these are a tough
cell to kill.
They live in hypoxic environments, making
them very difficult to kill, and they love
glutamine.
They love glutamine, so you have to know that.
So, if most cancer cells obtain energy through
fermentation, what can we do?
One strategy is try to reduce fermentable
fuels and give them non-fermentable fuels.
So, what we do is we use calorie-restricted
ketogenic diets, therapeutic fasting, and
this
kind of thing that we’ve heard about today.
So here is a number of things about calorie
restriction.
The important thing here is that calorie restriction
and restricted keto reduce blood glucose levels,
a fermentable fuel, and elevate ketone bodies,
a non-fermentable fuel.
So, what we’re trying to do is just simply
take away the driving fuel that makes the
beast go, and giving it something that it
can’t use.
And also this enhances the mitochondria, in
normal mitochondria starts to make them healthier.
But I want to show you calorie restriction
(CR) in a mouse.
But CR in the mouse equates water only therapeutic
fasting, and we heard that from Dr. Group
this morning, which was very interesting.
So, when I talk about calorie restriction
in mice, if you want to get the same effect
you have to stop eating and just drink water,
alright?
Now we use ketogenic diets, oh this is a big
mystery, follow this diet, that diet, Atkins
diet, you know.
The thing of it is, it’s very low carbohydrate,
let me go back.
It’s a very low carb diet, but the carbs,
the proteins, and the fats all play a very
important role
in ketogenic, that’s not all the same.
Many different forms of ketogenic diets.
Important thing, don’t eat too much of this.
If you eat too much, you’ll get insensitivity,
make the damn tumor grow faster.
You have to—food is medicine.
If you don’t know how to use the medicine
you could harm yourself.
You need people that know
how to do this stuff.
So, the goal here is that if you want to manage
it, at least the first step in trying to manage
the disease, is we’ve got to lower the blood
sugar, and we’ve got to elevate the non-fermentable
ketones, and then we can slow this guy down.
I’m not saying we cure him or we resolve,
I just say we slow it down because if we can
slow it down we can make ‘em vulnerable
to other forms of attack, and I’ll show
you about that.
So, this is one of the first reports that
got our attention, by Linda Nebeling at Case
Western Reserve.
She took two little girls, hopeless cases,
brutalized, brutalized by the system.
Surgery, radiation, chemo, the poor little
kids lost their—so she put them on this
ketogenic diet and was able to keep one kid
alive for two more years.
They were supposed to be dead very quickly,
read the original paper.
And one of the kids was lost to follow-up.
This is the only study done in pediatric oncology,
that I know about, where they actually got
tremendous results.
They don’t do it.
We do it in epilepsy all the time, treating
kids, little kids with ketogenic diets, but
not in pediatric oncology.
It’s a tragedy in my point.
Now, because of Linda’s paper, we got very
excited.
So, we decided to say, “How are we going
to be able to do this?”
So, we just take these mice, put glioblastoma
or astrocytoma cells into their brain, and
then we wait a couple of days and then we
gave them calorie restriction, and said 40%
calorie restriction is like water only therapeutic
fasting.
And you can see this large tumor on the guy,
this is standard diet unrestricted, which
is a high carbohydrate diet, high carbs.
And this is the same diet, just restricted
40%, and we get anywhere a 65 to 85% reduction
in the size of the tumor.
Each square here is a mouse under a different
dietary condition.
So as glucose goes down ketones go up.
This is an evolutionarily conserved adaptation
to what happens when we stop eating.
Ketones go up, because the brain has to have
an energy if you’re taking away the glucose.
As glucose goes down the size of the tumor
goes down.
This was our work in the mouse, it has since
been replicated in human glioblastoma, human
breast cancer, colon cancer, all these different
cancers.
The higher your sugar, the faster the tumor
grows, the lower the sugar the slower the
tumor grows.
Why is that so hard for anyone to understand?
Why in oncology clinics, you give cake and
ice cream to the kids?
It’s clear, it’s been replicated over
and over again.