Dr. Stephen Phinney: How can I tell if I’m no longer insulin resistant?

Dr. Stephen Phinney: How can I tell if I’m no longer insulin resistant?

November 1, 2019 1 By William Morgan


That is a challenging question to answer.
We could tell you about
your glycemic control.
You know there’s certainly a range
of understanding your blood glucose,
and how much your blood glucose varies
in terms of you know, what is your average
blood glucose over a period of time
when measured by A1c.
In terms of insulin resistance,
I guess the gold standard
would be the clamp?
The glycemic clamp?
– There’s actually a sign,
a research test where you
infuse insulin in one arm
and you infuse glucose in the other arm
and you see how much glucose it takes
to overcome the effects of insulin.
– Sure.
– The more standard approach is to do
either a fasting insulin,
and a fasting glucose
in the morning and that
is a calculation called–
– A homeo–
– Homeostatic measure
of insulin resistance.
And that’s something that
can be done by any physician.
It’s a standard test
with just one blood test.
If you wanna be more
rigorous you could do a,
and we don’t advocate this,
have people drink either a
50 or 75 grams of glucose
and measure the body’s insulin
and glucose response
over either two hours,
up to five hours.
But the home IR is a pretty good test–
– Yeah, it’s been validated against–
– It’s been validated in our,
what was the reduction
in home IR at one year?
Was it like 60%?
– I don’t remember off the top of my head.
It was significantly reduced.
Unfortunately I don’t remember the number.
– It was a very large reduction.
– Yeah.
– And so those are the ways,
but if you were taking diabetes medication
for Type II diabetes, and
you’re off those medications,
and your blood glucose control is better,
and your hemoglobin A1c
is down significantly
you’re markedly, you’ve markedly
improved your insulin resistance.
That you can know for sure.